New Service at Protein Structure and Chemistry Core: Crystallizations with microseeding

Use of crystal seed stocks in high-throughput crystallization screenings to improve the chances of crystal formation. Microseeds can be dispensed either during sitting drop or microbatch-under-oil setups.

A state-of-the-art single-photon counting X-ray detector and a new goniometer have been installed. The new set-up allows:

  • In situ data collection
  • In situ crystal characterisation
  • Fast data collection and processing
  • Serial crystallography
  • Fragment screening for drug design
  • Easy and efficient in-house phasing
  • Small-molecule crystallography
  • Powder diffraction
  • New educational and training activities
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In situ crystal testing