A number of libraries are now available for use at the screening unit. Please contact use to discuss your needs.

Chemical Libraries

Libraries available on-site include:

  • The bioascent 12k small molecule library
    12000 compound representation of the diversity of a 125k commercial library for subsequent cherry-picking
  • The Microsource Discovery Spectrum small molecule library
    • 1600 approved drugs
    • >700 bioactive and natural compounds
  • Several smaller thematic collections in the range of ~500 and smaller numbers of similar compounds
  • A large fragment library ~10000 compounds is currently being selected for purchase and should be available soon

Genetic Screen Libraries

A number of smaller collections for murine RNAi and human RNAi approaches and pooled murine genome-wide Crispr approaches are also held.

Probe and Reporter Libraries in Gene Transfer Vectors

The unit develops and holds an expanding panel of AAV preps for multiplexed use in high-throughput fluorescence microscopy,  to allow parallel monitoring of cell signalling events and morphological changes, as well as optogenetic or RNAi-knockdown based actuation. New probes can be rapidly assembled and prepared or newly designed according to the needs of users.